<p class="MsoNormal"><span lang="EN-US">The eCRF
solution by Cerebellis is composed of Digitalis and ODM Designer:<o:p></o:p></span></p><p class="MsoListParagraphCxSpFirst" style="margin-left:18.0pt;mso-add-space:
auto;text-indent:-18.0pt;mso-list:l1 level1 lfo2;tab-stops:list 18.0pt"><!--[if !supportLists]--><span lang="EN-US">1.<span style="font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: &quot;Times New Roman&quot;;">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
</span></span><!--[endif]--><span lang="EN-US">Digitalis
is the interface to manage the subjects and enter the data,<o:p></o:p></span></p><p class="MsoListParagraphCxSpMiddle" style="margin-left:18.0pt;mso-add-space:
auto;text-indent:-18.0pt;mso-list:l1 level1 lfo2;tab-stops:list 18.0pt"><!--[if !supportLists]--><span lang="EN-US">2.<span style="font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: &quot;Times New Roman&quot;;">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
</span></span><!--[endif]--><span lang="EN-US">ODM
Designer is like a back office where it is possible to design a study and its
protocol (study events, forms, items …)<o:p></o:p></span></p><p class="MsoListParagraphCxSpLast" style="margin-left:18.0pt;mso-add-space:auto"><span lang="EN-US">&nbsp;</span></p><p class="MsoNormal"><span lang="EN-US">The
Digitalis system is composed of the following components and sub-components:<o:p></o:p></span></p><ul><li style="text-indent: -18pt;"><span lang="EN-US" style="font-family:Symbol;mso-fareast-font-family:Symbol;mso-bidi-font-family:
Symbol;mso-ansi-language:EN-US"><span style="font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: &quot;Times New Roman&quot;;">&nbsp; &nbsp; &nbsp; &nbsp;&nbsp;</span></span><!--[endif]--><span lang="EN-US">Account
validation<o:p></o:p></span></li><li style="text-indent: -18pt;"><span lang="EN-US" style="font-family:Symbol;mso-fareast-font-family:Symbol;mso-bidi-font-family:
Symbol;mso-ansi-language:EN-US"><span style="font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: &quot;Times New Roman&quot;;">&nbsp; &nbsp; &nbsp; &nbsp; &nbsp;</span></span><!--[endif]--><span lang="EN-US">Authentication<o:p></o:p></span></li><li style="text-indent: -18pt;"><span lang="EN-US" style="font-family:Symbol;mso-fareast-font-family:Symbol;mso-bidi-font-family:
Symbol;mso-ansi-language:EN-US"><span style="font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: &quot;Times New Roman&quot;;">&nbsp; &nbsp; &nbsp; &nbsp; &nbsp;</span></span><!--[endif]--><span lang="EN-US">Dashboard<o:p></o:p></span></li><li style="text-indent: -18pt;"><span lang="EN-US" style="font-family:Symbol;mso-fareast-font-family:Symbol;mso-bidi-font-family:
Symbol;mso-ansi-language:EN-US"><span style="font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: &quot;Times New Roman&quot;;">&nbsp; &nbsp; &nbsp; &nbsp; &nbsp;</span></span><!--[endif]--><span lang="EN-US">Documents<o:p></o:p></span></li><li style="text-indent: -18pt;"><span lang="EN-US" style="font-family:Symbol;mso-fareast-font-family:Symbol;mso-bidi-font-family:
Symbol;mso-ansi-language:EN-US"><span style="font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: &quot;Times New Roman&quot;;">&nbsp; &nbsp; &nbsp; &nbsp;&nbsp;</span></span><!--[endif]--><span lang="EN-US">Manage:<o:p></o:p></span></li></ul><p style="margin-left: 72pt; text-indent: -18pt;"><!--[if !supportLists]--><span lang="EN-US" style="font-family:&quot;Courier New&quot;;mso-fareast-font-family:&quot;Courier New&quot;;
mso-ansi-language:EN-US">o<span style="font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: &quot;Times New Roman&quot;;">&nbsp;&nbsp;&nbsp;
</span></span><!--[endif]--><span lang="EN-US">Accounts<o:p></o:p></span></p><p style="margin-left: 72pt; text-indent: -18pt;"><!--[if !supportLists]--><span lang="EN-US" style="font-family:&quot;Courier New&quot;;mso-fareast-font-family:&quot;Courier New&quot;;
mso-ansi-language:EN-US">o<span style="font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: &quot;Times New Roman&quot;;">&nbsp;&nbsp;&nbsp;
</span></span><!--[endif]--><span lang="EN-US">Administration<o:p></o:p></span></p><p style="margin-left: 72pt; text-indent: -18pt;"><!--[if !supportLists]--><span lang="EN-US" style="font-family:&quot;Courier New&quot;;mso-fareast-font-family:&quot;Courier New&quot;;
mso-ansi-language:EN-US">o<span style="font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: &quot;Times New Roman&quot;;">&nbsp;&nbsp;&nbsp;
</span></span><!--[endif]--><span lang="EN-US">Clinical
data<o:p></o:p></span></p><p style="margin-left: 72pt; text-indent: -18pt;"><!--[if !supportLists]--><span lang="EN-US" style="font-family:&quot;Courier New&quot;;mso-fareast-font-family:&quot;Courier New&quot;;
mso-ansi-language:EN-US">o<span style="font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: &quot;Times New Roman&quot;;">&nbsp;&nbsp;&nbsp;
</span></span><!--[endif]--><span lang="EN-US">Databases<o:p></o:p></span></p><p style="margin-left: 72pt; text-indent: -18pt;"><!--[if !supportLists]--><span lang="EN-US" style="font-family:&quot;Courier New&quot;;mso-fareast-font-family:&quot;Courier New&quot;;
mso-ansi-language:EN-US">o<span style="font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: &quot;Times New Roman&quot;;">&nbsp;&nbsp;&nbsp;
</span></span><!--[endif]--><span lang="EN-US">Study
design<o:p></o:p></span></p><ul><li style="text-indent: -18pt;"><span lang="EN-US" style="font-family:Symbol;mso-fareast-font-family:Symbol;mso-bidi-font-family:
Symbol;mso-ansi-language:EN-US"><span style="font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: &quot;Times New Roman&quot;;">&nbsp; &nbsp; &nbsp; &nbsp;&nbsp;</span></span><!--[endif]--><span lang="EN-US">Orders<o:p></o:p></span></li><li style="text-indent: -18pt;"><span lang="EN-US" style="font-family:Symbol;mso-fareast-font-family:Symbol;mso-bidi-font-family:
Symbol;mso-ansi-language:EN-US"><span style="font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: &quot;Times New Roman&quot;;">&nbsp; &nbsp; &nbsp; &nbsp; &nbsp;</span></span><!--[endif]--><span lang="EN-US">Subject
forms (eCRF) <o:p></o:p></span></li><li style="text-indent: -18pt;"><span lang="EN-US" style="font-family:Symbol;mso-fareast-font-family:Symbol;mso-bidi-font-family:
Symbol;mso-ansi-language:EN-US"><span style="font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: &quot;Times New Roman&quot;;">&nbsp; &nbsp; &nbsp; &nbsp; &nbsp;</span></span><!--[endif]--><span lang="EN-US">Subjects
list<o:p></o:p></span></li><li style="text-indent: -18pt;"><span lang="EN-US" style="font-family:Symbol;mso-fareast-font-family:Symbol;mso-bidi-font-family:
Symbol;mso-ansi-language:EN-US"><span style="font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: &quot;Times New Roman&quot;;">&nbsp; &nbsp; &nbsp; &nbsp; &nbsp;</span></span><!--[endif]--><span lang="EN-US">Queries</span></li><li style="text-indent: -18pt;"><span lang="EN-US" style="font-family:Symbol;mso-fareast-font-family:Symbol;mso-bidi-font-family:
Symbol;mso-ansi-language:EN-US"><span style="font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: &quot;Times New Roman&quot;;">&nbsp; &nbsp; &nbsp; &nbsp;&nbsp;</span></span><!--[endif]--><span lang="EN-US">User
profile<o:p></o:p></span></li></ul>